V d V t = P A C O 2 − P e C O 2 P A C O 2 Ī common step is to then presume that the partial pressure of carbon dioxide in the end-tidal exhaled air is in equilibrium with that gas' tension in the blood that leaves the alveolar capillaries of the lung. The original formulation by Bohr, required measurement of the alveolar partial pressure P A. The Bohr equation is used to quantify the ratio of physiological dead space to the total tidal volume, and gives an indication of the extent of wasted ventilation. Figure 3B: this figure shows the potential tidal volume reduction when reducing the instrumental dead space to keep constant alveolar ventilation (4.7L/min) for a constant respiratory rate.For example, for a respiratory rate of 20/min (blue lines), the tidal volume required is 7.5 ml/kg PBW with the highest dead space and 5. It differs from anatomical dead space as measured by Fowler's method as it includes alveolar dead space. This is given as a ratio of dead space to tidal volume. The Bohr equation, named after Danish physician Christian Bohr (1855–1911), describes the amount of physiological dead space in a person's lungs. Not to be confused with the Bohr model or the Bohr effect.
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